Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

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Question:
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

1.copies of the gene with an altered sequence so that a restriction site is inserted

2.mutagenized copies of a gene

3.short sequences that will hybridize only to a specific base sequence

4.PCR-amplified variable numbers of tandem repeats (VNTRs)

Posted Date:-2021-03-07 10:53:13

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